Public Health

What Do COVID-19 Antibody Results Mean?

Khang T. Vuong, MHA
Khang T. Vuong, MHA6 Apr 2022
Different Types of COVID-19 Antibody Tests
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When to Get an Antibody Test
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What Your COVID-19 Antibody Test Results Mean
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Getting an Antibody Test After COVID-19 Exposure
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Accuracy of COVID-19 Antibody Tests
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Vaccination and COVID-19 Antibodies
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Checking COVID-19 Vaccine Efficacy with an Antibody Test
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The two main types of COVID-19 tests are diagnostic tests (PCR and antigen) and antibody tests. While diagnostic tests detect an active COVID-19 infection, antibody tests detect past infection with COVID-19.

Different Types of COVID-19 Antibody Tests

There are two main types of tests for COVID-19: diagnostic tests and antibody tests. 

Diagnostic tests can detect whether or not you have an active infection of COVID-19. There are two categories of diagnostic tests, molecular PCR tests, and rapid antigen tests. 

Antibody (serology) tests detect a previous infection with COVID-19 but do not show if you are currently infected. If you had coronavirus, your immune system may have produced antibodies to fight the infection. Antibody tests are completed by collecting a blood sample and results are typically available within 1-3 days. 

When to Get an Antibody Test

In the graphic below, we outline when you should consider getting a PCR, antigen, and antibody test for COVID-19. If you want to see if you were previously infected with COVID-19, you should get an antibody test. 

If you need a test for travel purposes, most states ask for a PCR test; however, a few states will accept an antigen test as well. If you had recent exposure to someone who has COVID-19 or has symptoms, you should get a diagnostic test. An antigen test will give you results faster, but the results of a PCR test are more accurate. If you get a negative antigen test, your provider may want you to confirm these results by getting a PCR test as well. 

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Khang T. Vuong, MHA

Khang T. Vuong received his Master of Healthcare Administration from the Milken Institute School of Public Health at the George Washington University. He was named Forbes Healthcare 2021 30 under 30. Vuong spoke at Stanford Medicine X, HIMSS conference, and served as a Fellow at the Bon Secours Health System.

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