Prescriptions

The 7 Most Effective Antibiotics for Skin Infections in 2024

Mira Research Team
Mira Research Team1 Jan 2024
Reviewed and Fact Checked ✔️

To effectively control and treat skin infections, several antibiotics stand out due to their efficacy, most notably: cephalexin, dicloxacillin, clindamycin, amoxicillin/clavulanate, trimethoprim/sulfamethoxazole, doxycycline, and minocycline. These antibiotics have proven veritable powerhouses, with varied advantages and drawbacks subject to side effects, cost, and accessibility. For instance, cephalexin is widely prescribed due to its potency against a variety of bacterial infections, but it also comes with potential side effects like stomach upset and diarrhea (Mayo Clinic). On the other hand, dicloxacillin is relatively well-tolerated but tends to be more expensive, limiting its accessibility for some patients (WebMD). 

AntibioticBest ForCommon Side EffectsCost (w/o Insurance)Insurance Coverage
CephalexinStaphylococcus and Streptococcus Skin InfectionsStomach upset, DiarrheaOver $50Generally covered
DicloxacillinImpetigo and Other Skin InfectionsStomach upset, Mild rashMore expensive than some antibioticsNot specified
ClindamycinSerious InfectionsDiarrhea, Possible rash, Intestinal problemsUpwards of $100Most plans cover
Amoxicillin/ClavulanateBroad-Spectrum TreatmentMild diarrhea, Nausea, HivesVariesTypically covered
Trimethoprim/SulfamethoxazoleMRSA InfectionsNausea, Vomiting, Skin rashesCost-effectiveCovered by most plans
DoxycyclineAcne and RosaceaSunlight sensitivity, Skin rashesAffordable to expensiveGenerally covered
MinocyclineAcne VulgarisDizziness, Lightheadedness, Skin discolorationVariesWidely covered

Types of Skin Infections

Skin infections may be bacterial, fungal or viral, each distinguished by its causative agents and characteristics. Bacterial skin infections often manifest as boils, cellulitis, or impetigo, typically caused by Staphylococcus or Streptococcus bacteria. Additionally, fungal infections, such as athlete's foot or ringworm, are usually instigated by fungi which thrive in warm, moist environments. Viral skin infections like herpes simplex and shingles are triggered by various viruses and usually present as painful, blister-like lesions (American Academy of Dermatologists). Understanding the nature of your skin infection is crucial for determining the most effective treatment approach.

Symptoms and Causes of Skin Infections

Generally, skin infections may cause itchiness, redness, warmth, swelling, or even pus-filled lesions, but the exact symptoms depend on the type of skin infection at play. They are often caused by invasive microorganisms that have breached the skin's protective barrier, possibly through a cut, scrape, or bug bite. In some cases, regular skin bacteria may also cause an infection if they multiply uncontrollably, often due to a weakened immune system or poor hygiene practices (Centers for Disease Control and Prevention). Identifying these symptoms and understanding their causes can aid in early detection and treatment, ultimately ensuring a faster recovery pace.

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Mira Research Team

The Mira Research team conducts original data and medical research on the most applicable topics of today and translates them into easy-to-understand articles to educate the public. Each of our articles is carefully reviewed and curated with interviews and opinions from medical experts, public health officials, and experienced administrators. The team has educational backgrounds from New York University, the University of Virginia, more.

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